Assessing infectivity of emerging enveloped viruses in wastewater and sewage sludge: relevance and procedures.

Chaqroun A., Bertrand I., Wurtzer S., Moulin L., Boni M., Soubies S., Boudaud N., Gantzer C. (2024) ., 2024. may. 

Accepted in Science of the Total Environment (28/05/2024).

Eaux usées et agents de la menace NRBC. L’actualité chimique, mars 2024, 493, 2024 : 9-12.

Boni M., Magisson F., Gorgé O., GIS OBEPINE, Mullot J.-U.

Implementation of a National Wastewater Surveillance System in France as a Tool to Support Public Authorities During the Covid Crisis: The Obepine Project, in: The Handbook of Environmental Chemistry. Springer, Berlin, Heidelberg, pp. 1–29

Boni M., Wurtzer, S., Mouchel, J.M., Maday, Y., Le Guyader, S.F., Garry, P., Bertrand, I., Cluzel, N., Courbariaux, M., Wang, S., Gantzer, C., Maréchal, V., Moulin, L., 2023. sept. 2023

Toward better monitoring of human noroviruses and F-specific RNA bacteriophages in aquatic environments using bivalve mollusks and passive samplers: A case study

Do Nascimento J. Bichet M., Challant J., Loutreul J. et Obepine consortium, sept. 2023

Highly efficient and sensitive membrane-based concentration process allows quantification, surveillance, and sequencing of viruses in large volumes of wastewater

El Soufi G., Jorio LD., Gerber Z., Cluzel N., Assche JV., Rohr O., et Obepine consortium, juin 2023


Implementation of a National Wastewater Surveillance System in France as a Tool to Support Public Authorities During the Covid Crisis: The Obepine Project

Boni M. et Obepine consortium.

Springer, 2023. 

“Wastewater-based epidemiology: current status and future of an alternative epidemiological method for detecting and tracking epidemics”

Maréchal V., Boni M., Maday Y., Cluzel N., Obepine consortium.

Hal Open Science, 2023.

SARSCoV2 wholegenome sequencing using oxford nanopore technology for variant monitoring in wastewaters

Barbe L., Schaeffer J., Besnard A., Jousse S., Wurtzer S., Moulin L., Obepine consortium (Boni M.), Le Guyader S., Desdouits M.

Frontiers In Microbiology, 2022,13, 889811 (14p.)

“The French Armed Forces Biomedical Research Institute (IRBA) and wastewater-based epidemiology: Applicability and relevance in armed forces

Boni M., Gorgé O., Mullot J.U., Wurtzer S., Moulin L., Maday Y., GIS OBÉPINE, Canini F., Chantre M., Teyssou R., Maréchal V., Janvier F., Tournier J.N.
Bulletin de l’Académie Nationale de Médecine, 2022, ISSN 00014079.

Development of passive samplers for the detection of SARSCoV2 in sewage and seawater: Application for the monitoring of sewage

Vincent-Hubert F., Wacrenier C., Desdouits M., Jousse S., Schaefer J., Le Mehaute P., Nakache Danglot F., Obepine consortium, Le Guyader S.

Science of The Total Environment, 2022, 155139, ISSN 00489697.

“Reduction in SARSCoV2 Virus Infectivity in Human and Hamster Feces

Wurtzer, S., Lacote, S., Murri  S., Marianneau P., MonchatreLeroy E., Boni M., Ferraris O., Maday Y., Kébé O., Dia N., Peyrefitte C., Sokol H., Obepine consortium, Moulin L, Maréchal V.

Viruses 2022, 14, 1777.

“From Alpha to Omicron BA.2 : New digital RTPCR approach and challenges for SARSCoV2 VOC monitoring and normalization of variant dynamics in wastewater”

Wurtzer S., Levert M., Dhenain E., Accrombessi H., Manco S., Fagour N., Goulet M., Boudaud N., Gaillard L., Bertrand I., Challant J., Masnada S., Azimi S., Gillon-Ritz M., Robin A., Mouchel J.M., Obepine consortium, Moulin L.

Science of The Total Environment,Volume 848, 2022,157740, ISSN 00489697.

“SARS-CoV-2 Variability in Patients and Wastewaters—Potential Immuno-Modulation during the Shift from Delta to Omicron”

Chaqroun A., Hartard C., Josse T., Taverniers A., Jeulin H., Gantzer C., Murray J-M., Obepine consortium, Bertrand I, Schvoerer E.

Biomedicines. 2022 ; 10(9):2080.

“First detectionon of Monkeypox virus genome in sewersheds in France. The potential of wastewaterbased epidemiology for monitoring emerging disease”

Wurtzer S., Levert M., Dhenain E. Boni M., Tournier JN., Londinsky N., Lefranc A., Ferraris O., Moulin L.

Environmental Science & Technology LeEers 2022, 9, 11, 991996.

Implementation of a national wastewater surveillance system in France as a tool to support public authorities during the COVID crisis: the Obepine project

Boni M., Wurtzer S. et al.

in The Handbook of Environmental Chemistry (698) Wastewater Surveillance of Covid19: Perspective, Problem, Prevalence and Precedence (Springer), (Series Editors: Barceló, Damià, Kostianoy, Andrey G.), (accepté, en cours de publication), 2022.

“SARS-CoV-2 genome quantification in wastewaters at regional and city scale allows precise monitoring of the whole outbreaks dynamics and variants spreading in the population
Wurtzer, S., Waldman, P., Levert, M., Cluzel, N., Almayrac, J. L., Charpentier, C., Masnada, S., Gillon-Ritz, M., Mouchel, J. M., Maday, Y., Boni, M., OBEPINE Consortium, AP-HP Virologist Group, Marechal, V., & Moulin, L., 2022, The Science of the total environment, 810, 152213.

A flexible smoother adapted to censored data with outliers and its application to SARS-CoV-2 monitoring in wastewater
Courbariaux M., Cluzel N., Wang, S. Maréchal V., Moulin L., Wurtzer S., Obépine consortium,  Mouchel J.-M., Maday Y., Nuel G.
Frontiers in Applied Mathematics and Statistics, 2022, Vol 3,,


A nationwide indicator to smooth and normalize heterogeneous SARS-CoV-2 RNA data in wastewater
Cluzel N., Courbariaux M., Wang S., Moulin L., Wurtzer S., Bertrand I., Laurent K., Monfort P., Gantzer C., Le Guyader S., Boni M., Mouchel
J.-M., Maréchal V., Nuel G., Maday Y.
Environment International, 2022/1/1, Volume 158, Pages : 106998

L’épidémiologie basée sur les eaux usées, un outil innovant pour le suivi sanitaire des populations : l’exemple du réseau Obépine, sentinelle de l’épidémie de Covid-19 / Wastewater-based epidemiology, an innovative tool for population health monitoring: example of the Obépine network, sentinel of the Covid-19 outbreak
Moulin L., Boni M., Cluzel N., Gary P., Le Guyader Soizick, Levert M., Maday Y., Marechal V., Mouchel J.-M., Wang S., Wurtzer S. Techniques Sciences Méthodes, Spécial(COVID-19), 21-30. Publisher’s official version :

Monitoring the propagation of SARS CoV2 variants by tracking identified mutation in wastewater using specific RT-qPCR
Wurtzer S., Waldman P., Levert M., Mouchel J.-M., Gorgé O., Boni M., Maday Y., OBEPINE consortium, Marechal V., Moulin L.

Maladies infectieuses virales vues au travers des eaux usées

Wurtzer S., Maréchal V., Bertrand I., Boni M., Le Guyader S., Moulin L., Maday Y., Gantzer C., Mouchel J-M.

Virologie, 2021, Volume 25, Numéro 1, 8-11: doi:10.1684/vir.2021.0881

Several forms of SARS-CoV-2 RNA can be detected in wastewaters : implication for wastewater- based epidemiology and risk assessment

Wurtzer S., Waldman P., Ferrier-Rembert A., Frenois-Veyrat G., Mouchel JM., Boni M., Maday Y., OBEPINE consortium, Marechal V. & Moulin L.

Soumis à Water Research et disponible en archive ouverte depuis le 22/12/2020, accepté le 18/04/2021 :

Epidemiological surveillance of SARS-CoV-2 by genome quantification in wastewater applied to a city in the northeast of France: comparison of ultrafiltration and protein precipitation based-methods

Bertrand I., Challant J., Jeulin H., Hartard C., Mathieu L., Lopez S., Scientific Interest Group Obépine, Schvoerer E., Courtois S., Gantzer C.

International Journal of Hygiene and Environmental Health, Soumis le 27 Août 2020, accepté le 12 Janvier 2021, publié le 31 Janvier 2021

“Surveillance des eaux usées du porteavions Charles de Gaulle dans le cadre de la pandémie SARSCOV2″

Bulletin de l’Association Technique Maritime et Aéronautique. Numéro 120. 2021.

Epidemiological Forecasting with Model Reduction of Compartmental Models. Application to the COVID-19 pandemic

Bakhta A., Thomas Boiveau, Maday Y., Mula O.

Biology 2021, 10, 22., Soumis le 3 Novembre 2020, accepté le 23 Décembre 2020, publié le 31 Décembre 2020

“Can shellfish be used to monitor SARSCoV2 in the coastal environment?”

Desdouits M. et al.

Sci Total Environ. 2021.

“Obepine : A french experiment to monitor the Covid-19 iepidemic through wastewater”

Maréchal V., Moulin L., Maday Y., Boni M., teyssou R., Wurtzer S., Mouchel J-M., Bertrand I., Gantzer C., Le Guyader S.

Bulletin de l’Acadamédie Vétérinaire de France, 2021, Vol 174.

“Somatic coliphages are conservative indicators of SARSCoV2 inactivation during heat and alkaline pH treatments

Varbanov M., Bertrand I., Philippot S., Retourney C., Gardette M., Hartard C., Jeulin H., Duval R-E, Loret J-F, Schvoerer E, Gantzer C.

Sci Total Environ 797:149112. doi:10.1016/j.scitotenv.2021.149112

OBEPINE, (2021)

Evaluation of 17th March 2020 lockdown effect on SARS-CoV-2 dynamics through viral genome quantification in Greater Paris wastewaters , France, 5 March to 23 April 2020

Wurtzer S., Marechal V., Mouchel J-M., Maday Y., Teyssou R., Richard E., Almayrac J-L., Moulin L.

Eurosurveillance 2020;25(50):pii=2000776.

Article soumis le 28 Avril 2020, accepté le 20 Septembre 2020, publié le 17 Décembre 2020

Le commentaire publié par Science à la suite de la soumission de notre premier papier (Wurtzer et al, Eurosurveillance).


Sorbonne Université

4 place Jussieu, 75252 Paris  Cedex 05